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2.2 Combination treatment with low-dose cumene hydroperoxide and RITA Nursing LE rat pups were randomly assigned to receive subcutaneous injections in the nape of the neck with either PBS, low-dose cumene hydroperoxide, the P53 activator RITA (Reactivation of p53 and Induction of Tumor cell Apoptosis) (S2781, Selleck Chemicals, Houston, TX), or a combination of low-dose cumene hydroperoxide and RITA

Data collection Data were retrospectively collected from electronic medical records

The donor compartment was filled with 2.5 mg (200 L) of quercetin-loaded niosomal gel, while the receptor compartment was filled with 12 mL of PBS at pH 6.4

& Zama, I