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injections of b12 are given in the treatment of Shots at Home: How, Where & How Often to Inject Yourself B12 Injection Dosage and Frequency:
Description
They may need to rely on supplements or vitamin B12 injections to maintain adequate levels, and the frequency of supplementation will affect how long the vitamin stays in the body

Other culprits include intestinal parasites or bacterial overgrowth

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B-12 Compliance Injection package insert / prescribing information for healthcare professionals