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doi: 10.3390/biomedicines11082309, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 120.Repetti CSF, Rueda JR, Porto CD, Franco RP, Girio RJS, Manhoso FFR, et al
The two major precursors to acetyl-CoA in the nuclear-cytoplasmic compartment are citrate and acetate, which are processed to acetyl-CoA by ATP-citrate lyase (ACLY) and acyl-CoA synthetase short-chain 2 (ACSS2), respectively
It occurs in two forms, known as D and L, but only L-carnitine is active in the body and is the form found in food
