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Biomed Pharmacother 143:112125

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This is partly a result of insulins effects on hepatic GHR expression, and partly a post-receptor signaling effect as unraveled by extensive animal studies (reviewed in (60)

The findings presented strong evidence of acute neurological impairments, heightened neuroinflammation, microgliosis in the gray matter, abnormalities in microstructural vasculature, as well as elevated levels of plasma total tau and neurofilament light [200]
