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The Role of Progesterone in Unopposed Estrogen Estrogen does not act alone

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During the early stages of cellular proliferation, Cyclin B/cyclin-dependent kinase 1 (CDK1) enhances the phosphorylation levels of DRP1 at Ser585 and Ser616, thereby increasing the GTPase activity of DRP1 and promoting mitochondrial fission [96, 97]
