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Cluster determinant 36 (CD36), an essential glycoprotein responsible for fatty acid uptake, exacerbates oxidative stress and induces the apoptosis of -cells under hyperglycemic conditions through pathways involving ceramide, thioredoxin-interacting protein (TXNIP), and Rac1-nicotinamide adenine dinucleotide phosphate oxidase (NOX)-mediated redoxosome formation

J Pediatr 2006;148:6528 [DOI] [PMC free article] [PubMed] [Google Scholar] 2.Blackford MG, Felter T, Gothard MD, et al

miRNAs also control mitochondrial dynamics and redox balance, both essential for metastatic potential and treatment adaptation [119]