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Conversely, concomitant use of nicotine and rifabutin, a CYP2B6 inducer, will result in a modest increase in mediated metabolism of the substrate, potentially leading to a reduction in serum concentration and/or therapeutic effect ( In vitro research suggests that varenicline does not appear to influence the pharmacokinetics of substances that are primarily metabolised by CYP enzymes

Karimzadeh M, Rashidi L, Ganji F (2017) Mesoporous silica nanoparticles for efficient rivastigmine hydrogen tartrate delivery into SY5Y cells
Ho CK, Choi S, Siu PM, Benzie IF (2013) Genoprotection and genotoxicity of green tea ( Camellia sinensis ): are they two sides of the same redox coin
