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In 1993, the first large, randomized, double-blind, primary prevention trial to investigate the potential cancer prevention benefits of supplementing with vitamin E, selenium and -carotene was conducted, and the cocktail has been found to dramatically lower mortality from gastric cancer (159)

Part of this study was carried out at the National Institute for Health and Care Research (NIHR) Leicester BRC (NIHR203327)

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Du, Kleitz [65] have successfully synthesized large-scale disulfide bond-containing MONs with varied sizes, morphologies, and pore sizes