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In fact, the thioldisulfide pool is thought to be primarily responsible for intracellular redox homeostasis and these reactions are important both for antioxidant defense and redox regulation of cell signaling (108)

[DOI] [PubMed] [Google Scholar] 197.Benyahia B., Huguet S., Declves X., Mokhtari K., Crinire E., Bernaudin J.F., Scherrmann J.M., Delattre J.Y

When the newly synthesized NRF2 molecule binds to the Keap1 molecule via the ETGE motif, it is in the open conformation

Global Status Report on Alcohol and Health 2018
