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Moreover, the hydrazone bond formed between the cyanine hydrazide and protein carbonyls is usually sensitive to acidic environment and narrow pH range conditions are required to optimize the efficient binding of cyanine-hydrazide fluorescent dye to its carbonyl targets

KYNA also helps reducing excitotoxicity caused by excessive glutamate release, which occurs due to the compensatory presynaptic glutamate release, a direct consequence of NMDAR hypofunction [3,87,88,89]

It is a synthetic peptide that has been studied primarily in preclinical and experimental settings

We also were classically taught that hyperhidrosis in small children was primarily palmar, but now we are finding that these children have sweating on the palms, soles, and sometimes in the axilla