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10.1016/j.biopha.2019.108876 57 MolagodaI

10.1136/annrheumdis-2018-213299 Ann Rheum Dis

Recently, researchers characterized a translocation involving histone demethylase KDM5A that resulted in fusion of the H3K4me3-binding PHD finger of KDM5A to the transcriptional activator NUP98, a common leukemia translocation partner, in an acute myeloid leukemia patient (Islam et al
Whereas investigators originally postulated that this transporter exported FeS clusters for incorporation into cytosolic proteins [2], proteins involved in the early steps of mammalian FeS cluster biogenesis are also found in the cytosol [23,4851] (Figure 3)
