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Kinetic stabilization of the -synuclein protofibril by a dopamine--synuclein adduct

In order to evaluate the impact of longer term, oral GSH supplementation on GSH status and in vivo oxidation status, this study performed the first randomized, double-blinded, placebo-controlled trial of orally administered GSH in healthy, adult humans

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It is reported that 5-ASA ameliorates UC in mice through dual mechanisms of preserving intestinal epithelial barrier integrity and modulating gut microbiota composition, with concomitant suprpression of JNK and p38 MAPK phosphorylation in colonic macrophages (Qu et al., 2017