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however, it has also been established that 2-oxo acid dehydrogenases, particularly pyruvate dehydrogenase complex (PDC) and 2-oxoglutarate dehydrogenase complex (OGDHC, also known as ketoglutarate dehydrogenase), are oxidant generators under permissive conditions and are themselves subject to redox modifications [4-9]

If children are not treated promptly with intravenous glucose, they progress to coma and death [21]