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Identification of novel curcumin-interacting proteins by an in vitro binding assay followed by a mass analysis In order to elucidate the signaling pathway that curcumin acts on to inhibit leukemic cell growth, we immobilized curcumin on epoxy-sepharose beads 17 and performed an in vitro binding assay using the lysate isolated from proliferating K562 cells

Large-scale, randomized controlled trials are critically needed to establish definitive efficacy for specific clinical indications and to compare these peptides with established therapies