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Spine 20 (11), 13071314
Antioxidants 7 (9), 110
Articular cartilage is primarily composed of chondrocytes and an extracellular matrix (ECM), which consists mainly of type II collagen and proteoglycans ( Synovial inflammation and immune dysregulation are also characteristic of OA
Notably, a recent study identified copper-associated proteotoxic stress [8] that may also be involved in the pathogenesis of CVD
