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In several previously published studies, Pycnogenol was shown to improve circulation in small blood vessels in the body, like the very fine micro vessels in the fingertips or in the retinal capillaries of the eye (31, 46)

The indices of ground glass opacities (GGOI) and reticular changes (fibrosis index (FIBI)) on HRCT, quantified as described previously 19 , remained stable (Supplementary Fig

This mechanism is enhanced by the application of exosomes Exosomes are micro-vesicles, about 1/1000th the size of a normal cell

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