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An elevated ferritin eliminated iron deficiency or occult bleeding, while a high lactate dehydrogenase and hyperbilirubinemia suggested hemolysis

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If low or low-normal, use higher dose supplementation or injectable b12

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Previous work has reported relatively increased Firmicutes and Proteobacteria and decreased Bacteroidetes in mice on an HFD, regardless of concomitant obesity (weight gain was minimized using a RELM knockout mouse 78 ) 78,79

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