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Description
Hypoxia-induced inhibition of propylhydroxylase enzymes leads to post-translational modifications in nucleic acids and proteins [1]

In chronic diabetic wounds, uncontrolled accumulation of reactive oxygen species (ROS) leads to localized irreversible oxidative damage and heightened inflammation 64

This allows assessment of tolerance before increasing to standard therapeutic doses of 1-2mg daily

Catherine Varney, caution that many of the products being promoted online have not undergone the rigorous testing required for approval by the U.S
