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Other Glutathione-Sparing Compounds Several nutrients help maintain glutathione levels by reducing its consumption or supporting its recycling: Vitamin C (ascorbic acid): Spares glutathione by scavenging reactive oxygen species directly, reducing the demand for glutathione as an antioxidant

In summary, we found that PRKN gene expression contributes to the network of available thiols in the cell, including by parkins participation in glutathione recycling, which involves a reversible, posttranslational modification at select cysteines