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Gnoni A, Longo S, Gnoni GV, Giudetti AM

Institutional Review Board Statement All the study procedures were found to be in accordance with the Helsinki Declaration of 1975/83

The most widely accepted hypothesis is that repeated microvascular injury or trauma to the penile tunica albuginea leads to abnormal wound healing and remodeling of the connective tissue into a fibrotic plaque [10,11]
