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Cerebrospinal fluid concentrations of N-acetylcysteine after oral administration in Parkinsons disease

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Neuroinflammation 17 , 39 (2020)

To overcome these limitations, we propose that future strategies must prioritize lesion-focused drug delivery, such as nanocarriers and triggerable prodrugs, alongside biomarker-guided treatment regimens to decouple efficacy from systemic risk, paving a credible path for the clinical application of Erastin-class agents in EMS
