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But I have come across similar reports describing something similar to a 48 hour half-life

Mechanism by which HDAC6 inhibits the acetylation of Phosphofructokinase 1 (PFK1) to promote proliferation of Vascular smooth muscle cells

Sci, USA 117 : 1223-1232 (2020)
Halmi NS, Parsons JA, Erlandsen SL, Duello T
