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Die Rezeptur basiert auf LCarnitintartrat und einer HPMCKapselhlle

TABLE 1 Potential candidates of drug repositioning for CIPN identified in preclinical studies Cytochrome-P 450 -epoxygenase 2J (CYP2J), High-mobility group box 1 (HMGB1), N -methyl-d-aspartate receptor (NMDAR), nuclear factor-erythroid-2-related factor 2 (Nrf2), organic anion-transporting polypeptide B2 (OATP1B2), organic cation transporter 2 (OCT2), phosphodiesterase (PDE), peroxisome proliferator-activated receptor gamma (PPAR), sphingosine 1-phosphate (S1P), store-operated calcium entry (SOCE), superoxide dismutase (SOD), potassium channel subfamily K member 2 (TREK1), transient receptor potential channel melastatin 8 (TRPM8)

After lip filler avoid pursing the lips for the first 24 hours, which includes using straws or water bottles, kissing/intimate oral actions, and/or smoking/vaping

doi: 10.1073/pnas.2012685118 191 PetersC