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[DOI] [PMC free article] [PubMed] [Google Scholar] 57.Sampey BP, Freemerman AJ, Zhang J, Kuan P-F, Galanko JA, OConnell TM, et al

The unit of analysis errors can occur when trials randomize participants to intervention or control groups in clusters but analyze the results using the total number of individual participants
Dosage should start at 50 mg/kg/day, and be increased slowly to a maximum of 3 g/day (30 mL/day) while assessing tolerance and therapeutic response

Meta-analysis 3.4.1
