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Moreover, MYC, increases mitochondrial export of acetyl groups as the form of citrate and the resulting acetyl-CoA contributes to histone acetylation by histone acetyltransferase GCN5 (117)

Clin Nutr ESPEN 46:510518 Sadlier C, Albrich WC, Neogi U, Lunjani N, Horgan M, OToole PW, OMahony L (2022) Metabolic rewiring and serotonin depletion in patients with postacute sequelae of Covid-19

Patients often exhibit structurally abnormal, swollen mitochondria with disrupted cristae, impaired mitochondrial recycling (a process called mitophagy), and chronically elevated levels of reactive oxygen species

Improved cardiovascular health by supplementation with selenium and coenzyme Q10: applying structural equation modelling (SEM) to clinical outcomes and biomarkers to explore underlying mechanisms in a prospective randomized double-blind placebo-controlled intervention project in Sweden