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The Cell Biology of Inflammasomes: Mechanisms of Inflammasome Activation and Regulation
Abdolmaleki F, Gheibi Hayat SM, Bianconi V, Johnston TP, Sahebkar A
These complexities are further underscored by a recent report by Soriani et al., which suggests that CD38 can act as a decoy for extracellular cGAMP, a mediator of innate immunity
ROS are a normal product of cell metabolism and are able to react with cellular components, such as DNA and membrane lipids, contributing to epithelial cell inflammation, airway hyperreactivity, tight junction barrier permeability, and lung injury [74,75]
