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Impure AOD-9604 or inconsistent sequencing can lead to unpredictable pharmacokinetic behavior, rendering any half-life calculations unreliable
[2] In DIO mice, 5-Amino-1MQ was reported to reduce body weight and white adipose mass and to lower plasma cholesterol, without a measured change in food intake

Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: metaepidemiological study
