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Integrative Potential and Clinical Insight From a functional medicine perspective, GLP-1, GLP-2, and VIP peptides could become adjunctive supports in MCAS and related conditions such as IBS, POTS, EhlersDanlos syndrome, chronic fatigue, and long COVID, where mast-celldriven neuroinflammation plays a central role

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Farge G, Falkenberg M

It concluded: SSRI use was associated with an almost 2-fold increase in the risk of developing UGIB [upper gastrointestinal bleed], especially among patients at high risk for GI bleeding (concurrent use of nonsteroidal anti-inflammatory or antiplatelet drugs)