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Similarly, in gastric ulcers, ALDH2 activation decreases inflammation and oxidative stress while suppressing ferroptosis-associated damage via inhibition of the nucleotide-binding domain, leucine-rich repeat and pyrin domain-containing protein 3 inflammasome (127)

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Zinc also improves insulin sensitivity and glycemic control because it contributes to reducing the synthesis of ROS under hyperglycemic conditions, thereby inhibiting the activation of oxidative stress pathways [12]

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