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Description
The largest Phase 2b trial used 0.25, 0.5, and 1 mg/day orally for 24 weeks
By inhibiting NNMT, 5-Amino-1MQ reduces the production of 1-methylnicotinamide (MNA), a metabolite that would otherwise deplete cellular nicotinamide pools
These observations help identify the actual source
67 68 Symptom monitoring Monitor symptoms regularly (eg, every two to three months) as they may reappear, even after several months, if injection frequency is reduced
