dihexa renal toxicity study Exacerbation of Dahl SS Hypertension and Damage by NOX2 in CD4+ T Cells Dihexa 1mL(10 mM in DMSO)

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A reduction in the mRNA level of inflammatory mediators (iNOS, IL-6, IFN-, and TNF-) and increased expression of HSP 70 and 90 and antioxidant proteins such as HO-1, NQO-1, glutathione reductase, glutathione peroxidase 2, and GST-pi were observed (Park et al., 2020)

At the two tested concentrations, treatment with both GHK and GHK-Cu did not significantly increase the IL-1, IL-8 and HSPA1A protein levels