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10.1002/emmm.201100134 21 Di Cesare MannelliL.ZanardelliM.BartolucciG.KariotiA.BiliaA.VannacciA.et al (2015)

J Pathol 241(3):337349

p53 inhibits the transcription of SLC7A11 by directly binding to its promoter in fibroblasts and certain cancer cells, which then affects the GPX4-regulated classical pathway and ultimately leads to ferroptosis (Fig

Discrepancies between the studies might be due to different concepts of studies as well as different formulations and dosages of carnitine used
