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This viewpoint originated from observations using PET and later BOLD-fMRI, which frequently detect a larger increase in local CMRglc compared to the increase in CMRO during neural activation (Fox et al., 1988)

Betaine Supplementation Modulates Betaine Concentration by Methylenetetrahydrofolate Reductase Genotype, but Has No Effect on Amino Acid Profile in Healthy Active Males: A Randomized Placebo-Controlled Cross-over Study. Nutrition Research (New York, N.Y.) , vol

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doi: 10.1111/ALL.15977 209 WilkinsonMHartAMilanSJSugumarK
