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In light of these concerns, sources such as seeds, herbs, genetically engineered plants, microalgae, macroalgae, and thraustochytrids are now being investigated for the development of vegan omega-3 PUFA commercial products (83)

Importantly, few randomized, placebo-controlled trials have assessed cognitive or disease-relevant clinical endpoints for nanoengineered phytochemical products, and existing trials are small or exploratory

If there are no comparators for a medicine, the PBAC will examine the economic analysis provided by the sponsor and reach a view as to whether the economic analysis (which must assume a cost to Government and therefore a price) justifies a recommendation for listing

As expected, patients with high SAAM scores exhibited low TMB, while those with low SAAM scores showed high TMB (Figure S6B)