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Not only that, but environmental factors can also play a role in destabilizing the gut microbiome and causing intestinal permeability

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Fe 3+ subsequently binds to transferrin (TF) or lactoferrin (LF) to form a TFFe 3+ complex, which is then recognized and internalized by transferrin receptor 1 (TFR1) on the cell surface (Zhao et al., 2025b)

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