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CIH, a core pathophysiological feature of OSA, acts as a key trigger for TGF- signaling and lung cancer progression, via two core regulatory mechanisms: first, CIH directly activates HIF-1, subsequently upregulating TGF- expression and driving Smad phosphorylation to induce myofibroblast differentiation and extracellular matrix (ECM) production (Liang et al., 2024)
Castor oil packs are often used for liver detoxification
