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10.1038/s41586-023-06328-6
Neither peptide has received regulatory approval as a therapeutic agent from the FDA, EMA, or other major regulatory bodies
Organ-on-a-chip in vitro models of the brain and the blood-brain barrier and their value to study the microbiota-gut-brain axis in neurodegeneration

Globisch D, Mnzel M, Mller M, Michalakis S, Wagner M, Koch S, Brckl T, Biel M, Carell T (2010) Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates
