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If both parents are in the lowest percentiles, based on our current understanding of the genes that regulate growth, their children would more likely be short compared with a child who comes from a family where both parents are tall

Generally, hydrophobic residues form essential contacts during protein-protein interactions, whereas acidic residues mediate long-range interactions with positively charged residues 50-53

This study aims to address known WD-associated cellular mechanisms in this cell culture model, increasing its significance for the development and testing of direct-acting therapeutic targets
