Frontiers
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Description
160 Despite their lack of FDA approval for fibromyalgia treatment, oral cyclobenzaprine (Flexeril, a skeletal muscle relaxant) and amitriptyline (a tricyclic antidepressant) are widely prescribed for fibromyalgia
Methods An alternative therapeutic strategy centers on genetically guided pro-dopamine regulation, which aims to transmodulate dopaminergic signaling to mitigate hyperalgesia
Xiao Y, Xu A, Law LS, et al
6 , 17 , 18 In addition, macrophage-derived growth arrest-specific 6 (GAS6) protein has been shown to promote stromal cell transdifferentiation through activation of the GAS6/AXL/NF-B signaling axis