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Moreover, as the negative effects of DMSO on the cell membrane are well known [1,2,3,15], in parallel to studies involving the direct addition of DMSO to the culture medium, a second method of administration was usedthe partial insertion of DMSO into polymerosomes (poly(ethylene glycol) and poly(lactide-co-glycolide) methyl ether block, PEG-PLGA) aimed at eliminating these potentially destructive effects

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Hippocampus mitochondrial MnSOD activation by a SIRT3 activator, honokiol, correlates with its deacetylation and upregulation of FoxO3a and PGC1 in a rat model of ammonia neurotoxicity