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It does mean patients should avoid treating BPC-157 as a casual wellness product

A puzzling observation was that although intracellular GSH levels are dependent on cysteine availability, GSH supplements also dampened bortezomib cytotoxicity

1 Introduction Periodontitis is a globally prevalent chronic inflammatory disease triggered by dysregulation of oral biofilm and host immune responses, serving as the primary cause of adult tooth loss ( A multi-platform analysis of human gingival crevicular fluid reveals that ferroptosis is an associated regulated cell death mechanism during the clinical progression of periodontitis ( Porphyromonas gingivalis can actively induce ferroptosis through multiple pathways ( This review systematically summarizes the molecular mechanisms of ferroptosis in periodontitis, with a focus on how dysregulated iron metabolism, reprogrammed lipid metabolism, and suppressed antioxidant defenses in the periodontal microenvironment regulate ferroptosis

Matsumoto T, Morizane T, Aoki Y, Yamasaki S, Nakajima M, Enomoto N, et al