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In addition, existing results have shown that iron overload results in the generation of ROS

This occurs by preventing the efflux of 2-KG from the mitochondrial matrix into the cytosol (Figure 2B)

[DOI] [PubMed] [Google Scholar] 29.Datta SR, et al

A single coadministration of subeffective doses of ascorbic acid and ketamine reverses the depressive-like behavior induced by chronic unpredictable stress in mice
