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In a large multicenter, double-blind randomized clinical trial of single euploid frozen embryo transfer, live birth was 58.5% in the receptivity-timed group versus 61.9% with standard timing, a non-significant difference [5]

In view of the considerable crosstalk between the molecular pathways in hepatic lipid homeostasis, inhibition of DNL is not a trivial task, even though it may constitute an attractive therapeutic target

Such defects in glucuronidation are common in the developing fetus and in newborns

Neither drug is available in the United States as of early 2021
