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The proteome of dormant Msm contains highly represented enzymes responsible for detoxification of methylglyoxal and other reactive aldehydes: aldehyde dehydrogenase (MSMEG_2597) and a glyoxalase family protein (MSMEG_5680, unique), as well as enzymes inactivating active nitrogen compounds [alkylhydroperoxide reductase (MSMEG_4891), dihydrolipoamide dehydrogenase (MSMEG_0903), dihydro lipoamide succinyltransferase (MSMEG_4283), and alkyl hydroperoxidase (MSMEG_4890)]

Ferroptosis and pyroptosis are connected through autophagy: a new perspective of overcoming drug resistance

siRNA against CIP4 (ID: s17814, 5-GGAGAAUAGUAAGCGUAAATT-3), FBP17 (ID: s22916, 5-CAACCUAAAAAGAACUCGATT-3), or Synd2 (ID: s22216, 5-AGAUGUUCUUAAGACCAAATT-3) were purchased from Ambion Inc

The only possible treatment is liver transplantation ( A new therapeutic approach to AIP is RNA interference-based therapy (Givosiran), which decreases aminolevulinic acid syntase mRNA levels