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Both hypoxia and hyperoxia trigger signaling events via mitochondrial-derived oxygen species (Fig

Quantitative real-time PCR (qRT-PCR) and Western blot assay Total RNA was extracted using Trizol reagent (Invitrogen) according to the manufacturers instructions protocol

In 2012, another coronavirus spread in the Middle East, causing the Middle East Respiratory Syndrome, leading to 2458 reported cases and a high mortality rate of 35% 2

Lancet Neurol 23:344381
