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Description
Hepcidin-induced reduction in iron content and pgc-1 Expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis

ROS stimulates the MAPK signal pathway, which is responsible for AP-1 formation (57)

Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors
Science 347 , 8386 (2015)