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These mDCs then transition into their mature state, becoming a prolific source of pivotal cytokines: IL-6, IL-12, IL-23, and TNF-

The significant increase in OsDJ-1 gene expression in response to MG suggests that MG may acts as a direct substrate for OsDJ-1 proteins and thus induce the expression of gene through substrate inducible mechanism 34

Thinking one could substitute for the other in a research context would be a catastrophic error in study design
