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Description
Targeting mitochondria-mediated ICD can release damage-associated molecular patterns (DAMPs) that promote dendritic cell (DC) maturation and T cell activation
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Peroxynitrite induced obvious nuclear distribution of NF-B p65 in SGNs and pretreatment with ebselen significantly reduced it, whereas the lack of GPX1 intensified the nuclear fluorescence of NF-B p65 in SGNs of peroxynitrite + gpx1 / group (Figure 8B)
