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While the [U- 13 C]serine tracing showed SAAR increased labeling of other fates of cysteine such as taurine, loss of hepatic PSAT1 uniquely attenuated the increased liver 13 C-GSH and 13 C-GSSG from [U- 13 C]glucose

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It is thought that after SCI, many neuroadaptation responses are implemented in dorsal horn, triggering central mechanisms which likely contribute to NP