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Moderna vaccine slightly more effective than Pfizer vaccine in preventing COVID-19 infection, hospitalization, and death Both vaccines are highly effective and either one is strongly recommended For immediate release: Wednesday, December 1, 2021 Boston, MA Compared with the Pfizer COVID-19 vaccine, the Moderna COVID-19 vaccine has a slightly lower risk of COVID-19 outcomes, including documented SARS-CoV-2 infection, symptomatic COVID-19, and COVID-19-related hospitalization, intensive care unit (ICU) admission, and death, over a 24-week period, according to a team of researchers from the CAUSALab at Harvard T.H